Hypothalamic–Pituitary–Testicular Disorders	

	The hypothalamic-pituitary-testicular axis is subject to a variety of influences. 
Impairment of gonadotrophin secretion may be the consequence of generalised diseases that affect the hypothalamus and pituitary (e.g. craniopharyngioma), or it may be an isolated deficiency in which secretion of LH and FSH is impaired; isolated hypogonadotrophic hypogonadism can be either congenital or, rarely, an acquired idiopathic defect.

See later:
• Isolated Hypogonadotrophic Hypogonadism
• Other Causes of Hypogonadotrophic Hypogonadism